Diagnosis of peripheral atherosclerosis is done by several tests:
- Pulse tests – lack of pulse or lowered pulse in the lower extremities.
- Doppler tests – a Doppler test for the lower extremities both at rest and on effort.
- In some circumstances it is preferable to continue further exploration with a CAT scan (a computer assisted tomography scan) where contrast material is injected in order to map the lower extremities and their disorders.
Once the diagnosis has been confirmed the continued course of treatment has to be chosen, while taking into consideration any other ailments the patient may have. If the disorder essentially affects the patient's quality of life, and based on the tests performed, catheterization could be considered – a surgical procedure usually done under a local anesthetic. During the catheterization, the narrowed and blocked blood vessels are expanded using the "over the wire" technique, in which stents and balloons are passed on a conductor which is inserted into the blood vessel (under imaging).
If the patient is not suited for catheterization, then further surgical intervention, such as atherosclerosis bypass surgery, could be considered, or alternatively treatment that combines both catheterization and surgery which would offer a less invasive medical solution.